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A co-ultramicronized palmitoylethanolamide/luteolin composite mitigates clinical score and disease-relevant molecular markers in a mouse model of experimental autoimmune encephalomyelitis
BACKGROUND: Persistent and/or recurrent inflammatory processes are the main factor leading to multiple sclerosis (MS) lesions. The composite ultramicronized palmitoylethanolamide, an endogenous N-acylethanolamine, combined with the flavonoid luteolin, PEALut, have been found to exert neuroprotective...
Autores principales: | Contarini, Gabriella, Franceschini, Davide, Facci, Laura, Barbierato, Massimo, Giusti, Pietro, Zusso, Morena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587257/ https://www.ncbi.nlm.nih.gov/pubmed/31221190 http://dx.doi.org/10.1186/s12974-019-1514-4 |
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