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Optimising trial designs to identify appropriate antibiotic treatment durations

BACKGROUND: For many infectious conditions, the optimal antibiotic course length remains unclear. The estimation of course length must consider the important trade-off between maximising short- and long-term efficacy and minimising antibiotic resistance and toxicity. MAIN BODY: Evidence on optimal t...

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Detalles Bibliográficos
Autores principales:	Pouwels, Koen B., Yin, Mo, Butler, Christopher C., Cooper, Ben S., Wordsworth, Sarah, Walker, A. Sarah, Robotham, Julie V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587258/ https://www.ncbi.nlm.nih.gov/pubmed/31221165 http://dx.doi.org/10.1186/s12916-019-1348-z

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