Cargando…

New STAT3-FOXL2 pathway and its function in cancer cells

BACKGROUND: The forkhead transcription factor (FOXL2) plays a crucial role in blepharophimosis-ptosis-epicanthus inversus syndrome (BPES), sex determination, ovary growth and development, and cell cycle regulation. Emerging investigations have focused on the downstream targets of FOXL2, while little...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Yangyang, Wu, Jun, Yang, Weiwei, Wang, Di, Zhang, Tianliang, Cheng, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587274/ https://www.ncbi.nlm.nih.gov/pubmed/31221094 http://dx.doi.org/10.1186/s12860-019-0206-3

Ejemplares similares

Foxl2 functions in sex determination and histogenesis throughout mouse ovary development
por: Garcia-Ortiz, José Elias, et al.
Publicado: (2009)

Functional study on new FOXL2 mutations found in Chinese patients with blepharophimosis, ptosis, epicanthus inversus syndrome
por: Zhou, Lu, et al.
Publicado: (2018)

Differential Apoptotic and Proliferative Activities of Wild-type FOXL2 and Blepharophimosis-ptosis-epicanthus Inversus Syndrome (BPES)-associated Mutant FOXL2 Proteins
por: KIM, Jae-Hong, et al.
Publicado: (2013)

FOXL2 directs DNA double-strand break repair pathways by differentially interacting with Ku
por: Jin, Hanyong, et al.
Publicado: (2020)

The Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours
por: Rosario, Roseanne, et al.
Publicado: (2012)

Sex determination and maintenance: the role of DMRT1 and FOXL2
por: Huang, Shengsong, et al.
Publicado: (2017)

FOXL1 overexpression is associated with poor outcome in patients with glioma
por: Chen, Ainian, et al.
Publicado: (2019)

FOXL2 is a Progesterone Target Gene in the Endometrium of Ruminants
por: Eozenou, Caroline, et al.
Publicado: (2020)

Functional Divergence of Multiple Duplicated Foxl2 Homeologs and Alleles in a Recurrent Polyploid Fish
por: Gan, Rui-Hai, et al.
Publicado: (2021)

Functional Studies of Novel FOXL2 Variants in Chinese Families With Blepharophimosis–Ptosis–Epicanthus Inversus Syndrome
por: Li, Fang, et al.
Publicado: (2021)

FOXL2 down-regulates vitellogenin expression at mature stage in Eriocheir sinensis
por: Li, Qing, et al.
Publicado: (2015)

FOXL2 expression might be a novel prognostic biomarker in patients with laryngeal squamous cell carcinoma
por: Ge, Jun, et al.
Publicado: (2020)

Maximal Expression of Foxl2 in Pituitary Gonadotropes Requires Ovarian Hormones
por: Herndon, Maria K., et al.
Publicado: (2015)

Uterine Foxl2 regulates the adherence of the Trophectoderm cells to the endometrial epithelium
por: Elbaz, Michal, et al.
Publicado: (2018)

Comparative Studies on Duplicated foxl2 Paralogs in Spotted Knifejaw Oplegnathus punctatus Show Functional Diversification
por: Du, Xinxin, et al.
Publicado: (2023)

Cancer overturned: Endometrioma mimicking granulosa cell tumor and the importance of FOXL2 analysis
por: Rosen, Emily R., et al.
Publicado: (2018)

Novel FOXL2 mutations in two Chinese families with blepharophimosis-ptosis-epicanthus inversus syndrome
por: Xue, Min, et al.
Publicado: (2015)

FOXL2 mutations in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome
por: Wang, Juan, et al.
Publicado: (2007)

Foxl1-Expressing Mesenchymal Cells Constitute the Intestinal Stem Cell Niche
por: Aoki, Reina, et al.
Publicado: (2015)

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target
por: Pierini, Stefano, et al.
Publicado: (2020)

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2
por: Nicol, Barbara, et al.
Publicado: (2019)

Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomics
por: Zhou, Jingjing, et al.
Publicado: (2022)

A novel FOXL2 mutation in a Chinese family with blepharophimosis, ptosis, epicanthus inversus syndrome
por: Tan, Hu, et al.
Publicado: (2015)

SUMOylation of the Forkhead Transcription Factor FOXL2 Promotes Its Stabilization/Activation through Transient Recruitment to PML Bodies
por: Georges, Adrien, et al.
Publicado: (2011)

The Forkhead Transcription Factor Foxl2 Is Sumoylated in Both Human and Mouse: Sumoylation Affects Its Stability, Localization, and Activity
por: Marongiu, Mara, et al.
Publicado: (2010)

Microhomology-Mediated Mechanisms Underlie Non-Recurrent Disease-Causing Microdeletions of the FOXL2 Gene or Its Regulatory Domain
por: Verdin, Hannah, et al.
Publicado: (2013)

An alternative miRISC targets a cancer‐associated coding sequence mutation in FOXL2
por: Shin, Eunkyoung, et al.
Publicado: (2020)

Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation
por: Wang, Wen-Chung, et al.
Publicado: (2014)

FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice
por: Marongiu, Mara, et al.
Publicado: (2015)

Home Sweet Home: a Foxl1(+) Mesenchymal Niche for Intestinal Stem Cells
por: Mah, Amanda T., et al.
Publicado: (2016)

Maternal metabolism affects endometrial expression of oxidative stress and FOXL2 genes in cattle
por: Lesage-Padilla, Audrey, et al.
Publicado: (2017)

The Genetic and Clinical Features of FOXL2-Related Blepharophimosis, Ptosis and Epicanthus Inversus Syndrome
por: Méjécase, Cécile, et al.
Publicado: (2021)

Adult‐type granulosa cell tumor of the ovary: a FOXL2‐centric disease
por: Pilsworth, Jessica A, et al.
Publicado: (2021)

Mutation of foxl1 Results in Reduced Cartilage Markers in a Zebrafish Model of Otosclerosis
por: Hawkey-Noble, Alexia, et al.
Publicado: (2022)

Overexpression of Forkhead Box L1 (FOXL1) Inhibits the Proliferation and Invasion of Breast Cancer Cells
por: Zhong, Jiateng, et al.
Publicado: (2017)

Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter
por: Escudero, Jean M, et al.
Publicado: (2010)

Novel FOXL2 mutations cause blepharophimosis‐ptosis‐epicanthus inversus syndrome with premature ovarian insufficiency
por: Yang, Xiao‐Wen, et al.
Publicado: (2018)

Identification of the forkhead transcriptional factor 2 (FOXL2) gene mutations in four Chinese families with blepharophimosis syndrome
por: Zhang, Li, et al.
Publicado: (2013)

Molecular cloning and analysis of gonadal expression of Foxl2 in the rice-field eel Monopterus albus
por: Hu, Qing, et al.
Publicado: (2014)

The transcription factor FOXL2 mobilizes estrogen signaling to maintain the identity of ovarian granulosa cells
por: Georges, Adrien, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2hlo0mtm70i4v1v1h77fa9cubi