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Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion
BACKGROUND: For species survival, the germline must faithfully transmit genetic information to the progeny. Transposable elements (TEs) constitute a significant threat to genome stability due to their mobility. In the metazoan germline, their mobilization is limited by a class of small RNAs called P...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587276/ https://www.ncbi.nlm.nih.gov/pubmed/31227013 http://dx.doi.org/10.1186/s13059-019-1736-x |