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Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity

OBJECTIVE: Obesity is associated with delayed insulin absorption upon subcutaneous (s.c.) dosing in humans. The aim of this study was to investigate whether alterations in depot structure and kinetics of the s.c. injection depot contribute to this delay. METHODS: Rats fed a high‐fat diet (HFD) and l...

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Detalles Bibliográficos
Autores principales:	Gradel, A. K. J., Porsgaard, T., Brockhoff, P. B., Seested, T., Lykkesfeldt, J., Refsgaard, H. H. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587326/ https://www.ncbi.nlm.nih.gov/pubmed/31275602 http://dx.doi.org/10.1002/osp4.326

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