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IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse models

Chronic hepatitis B virus (HBV) infection causes hepatitis, liver cirrhosis and hepatocellular carcinoma. Covalently closed circular DNA (cccDNA) is the sole viral transcription template and not affected by current treatment options, constituting a key determinant of HBV persistence. Novel therapeut...

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Detalles Bibliográficos
Autores principales:	Shen, Zhongliang, Liu, Jing, Wu, Jingwen, Zhu, Yuanfei, Li, Gaiyun, Wang, Jun, Luo, Mengjun, Deng, Qiang, Zhang, Jiming, Xie, Youhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587353/ https://www.ncbi.nlm.nih.gov/pubmed/31281514 http://dx.doi.org/10.7150/thno.35331

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