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Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study

BACKGROUND: Results from the HPTN 065 study showed that financial incentives (FI) were associated with significantly higher viral load suppression and higher levels of engagement in care among patients at HIV care sites randomized to FI versus sites randomized to standard of care (SOC). We assessed...

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Autores principales: El-Sadr, Wafaa M., Beauchamp, Geetha, Hall, H. Irene, Torian, Lucia V., Zingman, Barry S., Lum, Garret, Elion, Richard A., Buchacz, Kate, Burns, David, Zerbe, Allison, Gamble, Theresa, Donnell, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587372/
https://www.ncbi.nlm.nih.gov/pubmed/31194704
http://dx.doi.org/10.1097/QAI.0000000000001927
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author El-Sadr, Wafaa M.
Beauchamp, Geetha
Hall, H. Irene
Torian, Lucia V.
Zingman, Barry S.
Lum, Garret
Elion, Richard A.
Buchacz, Kate
Burns, David
Zerbe, Allison
Gamble, Theresa
Donnell, Deborah J.
author_facet El-Sadr, Wafaa M.
Beauchamp, Geetha
Hall, H. Irene
Torian, Lucia V.
Zingman, Barry S.
Lum, Garret
Elion, Richard A.
Buchacz, Kate
Burns, David
Zerbe, Allison
Gamble, Theresa
Donnell, Deborah J.
author_sort El-Sadr, Wafaa M.
collection PubMed
description BACKGROUND: Results from the HPTN 065 study showed that financial incentives (FI) were associated with significantly higher viral load suppression and higher levels of engagement in care among patients at HIV care sites randomized to FI versus sites randomized to standard of care (SOC). We assessed HIV viral suppression and continuity in care after intervention withdrawal to determine the durability of FI on these outcomes. SETTING: A total of 37 HIV test and 39 HIV care sites in the Bronx, New York, and Washington, DC, participated in the study. METHODS: Laboratory data reported to the US National HIV Surveillance System were used to determine site-level viral suppression and continuity in care outcomes. Postintervention effects were assessed for the 3 quarters after discontinuation of FI. Generalized estimation equations were used to compare FI and SOC site-level outcomes after intervention withdrawal. RESULTS: After FI withdrawal, a trend remained for an increase in viral suppression by 2.7% (−0.3%, 5.6%, P = 0.076) at FI versus SOC sites, decreasing from the 3.8% increase noted during implementation of the intervention. The significant increase in continuity in care during the FI intervention was sustained after intervention with 7.5% (P = 0.007) higher continuity in care at FI versus SOC sites. CONCLUSIONS: After the withdrawal of FI, findings at the 9-months postintervention withdrawal from this large study showed evidence of durable effects of FI on continuity in care, with trend for continued higher viral suppression. These findings are promising for adoption of such interventions to enhance key HIV-related care outcomes.
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spelling pubmed-65873722019-07-22 Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study El-Sadr, Wafaa M. Beauchamp, Geetha Hall, H. Irene Torian, Lucia V. Zingman, Barry S. Lum, Garret Elion, Richard A. Buchacz, Kate Burns, David Zerbe, Allison Gamble, Theresa Donnell, Deborah J. J Acquir Immune Defic Syndr Prevention Research BACKGROUND: Results from the HPTN 065 study showed that financial incentives (FI) were associated with significantly higher viral load suppression and higher levels of engagement in care among patients at HIV care sites randomized to FI versus sites randomized to standard of care (SOC). We assessed HIV viral suppression and continuity in care after intervention withdrawal to determine the durability of FI on these outcomes. SETTING: A total of 37 HIV test and 39 HIV care sites in the Bronx, New York, and Washington, DC, participated in the study. METHODS: Laboratory data reported to the US National HIV Surveillance System were used to determine site-level viral suppression and continuity in care outcomes. Postintervention effects were assessed for the 3 quarters after discontinuation of FI. Generalized estimation equations were used to compare FI and SOC site-level outcomes after intervention withdrawal. RESULTS: After FI withdrawal, a trend remained for an increase in viral suppression by 2.7% (−0.3%, 5.6%, P = 0.076) at FI versus SOC sites, decreasing from the 3.8% increase noted during implementation of the intervention. The significant increase in continuity in care during the FI intervention was sustained after intervention with 7.5% (P = 0.007) higher continuity in care at FI versus SOC sites. CONCLUSIONS: After the withdrawal of FI, findings at the 9-months postintervention withdrawal from this large study showed evidence of durable effects of FI on continuity in care, with trend for continued higher viral suppression. These findings are promising for adoption of such interventions to enhance key HIV-related care outcomes. JAIDS Journal of Acquired Immune Deficiency Syndromes 2019-07-01 2018-12-04 /pmc/articles/PMC6587372/ /pubmed/31194704 http://dx.doi.org/10.1097/QAI.0000000000001927 Text en Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Prevention Research
El-Sadr, Wafaa M.
Beauchamp, Geetha
Hall, H. Irene
Torian, Lucia V.
Zingman, Barry S.
Lum, Garret
Elion, Richard A.
Buchacz, Kate
Burns, David
Zerbe, Allison
Gamble, Theresa
Donnell, Deborah J.
Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study
title Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study
title_full Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study
title_fullStr Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study
title_full_unstemmed Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study
title_short Brief Report: Durability of the Effect of Financial Incentives on HIV Viral Load Suppression and Continuity in Care: HPTN 065 Study
title_sort brief report: durability of the effect of financial incentives on hiv viral load suppression and continuity in care: hptn 065 study
topic Prevention Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587372/
https://www.ncbi.nlm.nih.gov/pubmed/31194704
http://dx.doi.org/10.1097/QAI.0000000000001927
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