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Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence

BACKGROUND: Iterative computed tomography (CT) image reconstruction shows high potential for the preservation of image quality in diagnostic CT while reducing patients’ exposure; it has become available for low-dose CT (LD-CT) in high-end hybrid imaging systems (e.g. single-photon emission computed...

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Autores principales: Grosser, Oliver S, Ruf, Juri, Kupitz, Dennis, Czuczwara, Damian, Loewenthal, David, Thormann, Markus, Furth, Christian, Ricke, Jens, Denecke, Timm, Pech, Maciej, Kreissl, Michael C, Amthauer, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587393/
https://www.ncbi.nlm.nih.gov/pubmed/31258933
http://dx.doi.org/10.1177/2058460119856266
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author Grosser, Oliver S
Ruf, Juri
Kupitz, Dennis
Czuczwara, Damian
Loewenthal, David
Thormann, Markus
Furth, Christian
Ricke, Jens
Denecke, Timm
Pech, Maciej
Kreissl, Michael C
Amthauer, Holger
author_facet Grosser, Oliver S
Ruf, Juri
Kupitz, Dennis
Czuczwara, Damian
Loewenthal, David
Thormann, Markus
Furth, Christian
Ricke, Jens
Denecke, Timm
Pech, Maciej
Kreissl, Michael C
Amthauer, Holger
author_sort Grosser, Oliver S
collection PubMed
description BACKGROUND: Iterative computed tomography (CT) image reconstruction shows high potential for the preservation of image quality in diagnostic CT while reducing patients’ exposure; it has become available for low-dose CT (LD-CT) in high-end hybrid imaging systems (e.g. single-photon emission computed tomography [SPECT]-CT). PURPOSE: To examine the effect of an iterative CT reconstruction algorithm on image quality, image noise, detectability, and the reader’s confidence for LD-CT data by a subjective assessment. MATERIAL AND METHODS: The LD-CT data were validated for 40 patients examined by an abdominal hybrid SPECT-CT (U = 120 kV, I = 40 mA, pitch = 1.375). LD-CT was reconstructed using either filtered back projection (FBP) or an iterative image reconstruction algorithm (Adaptive Statistical Iterative Reconstruction [ASIR]®) with different parameters (ASIR levels 50% and 100%). The data were validated by two independent blinded readers using a scoring system for image quality, image noise, detectability, and reader confidence, for a predefined set of 16 anatomic substructures. RESULTS: The image quality was significantly improved by iterative reconstruction of the LD-CT data compared with FBP (P ≤ 0.0001). While detectability increased in only 2/16 structures (P ≤ 0.03), the reader’s confidence increased significantly due to iterative reconstruction (P ≤ 0.002). Meanwhile, at the ASIR level of 100%, the detectability in bone structure was highly reduced (P = 0.003). CONCLUSION: An ASIR level of 50% represents a good compromise in abdominal LD-CT image reconstruction. The specific ASIR level improved image quality (reduced image noise) and reader confidence, while preserving detectability of bone structure.
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spelling pubmed-65873932019-06-28 Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence Grosser, Oliver S Ruf, Juri Kupitz, Dennis Czuczwara, Damian Loewenthal, David Thormann, Markus Furth, Christian Ricke, Jens Denecke, Timm Pech, Maciej Kreissl, Michael C Amthauer, Holger Acta Radiol Open Research BACKGROUND: Iterative computed tomography (CT) image reconstruction shows high potential for the preservation of image quality in diagnostic CT while reducing patients’ exposure; it has become available for low-dose CT (LD-CT) in high-end hybrid imaging systems (e.g. single-photon emission computed tomography [SPECT]-CT). PURPOSE: To examine the effect of an iterative CT reconstruction algorithm on image quality, image noise, detectability, and the reader’s confidence for LD-CT data by a subjective assessment. MATERIAL AND METHODS: The LD-CT data were validated for 40 patients examined by an abdominal hybrid SPECT-CT (U = 120 kV, I = 40 mA, pitch = 1.375). LD-CT was reconstructed using either filtered back projection (FBP) or an iterative image reconstruction algorithm (Adaptive Statistical Iterative Reconstruction [ASIR]®) with different parameters (ASIR levels 50% and 100%). The data were validated by two independent blinded readers using a scoring system for image quality, image noise, detectability, and reader confidence, for a predefined set of 16 anatomic substructures. RESULTS: The image quality was significantly improved by iterative reconstruction of the LD-CT data compared with FBP (P ≤ 0.0001). While detectability increased in only 2/16 structures (P ≤ 0.03), the reader’s confidence increased significantly due to iterative reconstruction (P ≤ 0.002). Meanwhile, at the ASIR level of 100%, the detectability in bone structure was highly reduced (P = 0.003). CONCLUSION: An ASIR level of 50% represents a good compromise in abdominal LD-CT image reconstruction. The specific ASIR level improved image quality (reduced image noise) and reader confidence, while preserving detectability of bone structure. SAGE Publications 2019-06-20 /pmc/articles/PMC6587393/ /pubmed/31258933 http://dx.doi.org/10.1177/2058460119856266 Text en © The Foundation Acta Radiologica 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Research
Grosser, Oliver S
Ruf, Juri
Kupitz, Dennis
Czuczwara, Damian
Loewenthal, David
Thormann, Markus
Furth, Christian
Ricke, Jens
Denecke, Timm
Pech, Maciej
Kreissl, Michael C
Amthauer, Holger
Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence
title Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence
title_full Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence
title_fullStr Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence
title_full_unstemmed Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence
title_short Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications: effect on image quality, image noise, detectability, and reader’s confidence
title_sort iterative ct reconstruction in abdominal low-dose ct used for hybrid spect-ct applications: effect on image quality, image noise, detectability, and reader’s confidence
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587393/
https://www.ncbi.nlm.nih.gov/pubmed/31258933
http://dx.doi.org/10.1177/2058460119856266
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