Targeting PDGF‐mediated recruitment of pericytes blocks vascular mimicry and tumor growth

Aggressive tumor cells can adopt an endothelial cell‐like phenotype and contribute to the formation of a tumor vasculature, independent of tumor angiogenesis. This adoptive mechanism is referred to as vascular mimicry and it is associated with poor survival in cancer patients. To what extent tumor c...

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Detalles Bibliográficos
Autores principales: Thijssen, Victor LJL, Paulis, Yvette WJ, Nowak‐Sliwinska, Patrycja, Deumelandt, Katrin L, Hosaka, Kayoko, Soetekouw, Patricia MMB, Cimpean, Anca M, Raica, Marius, Pauwels, Patrick, van den Oord, Joost J, Tjan‐Heijnen, Vivianne CG, Hendrix, Mary J, Heldin, Carl‐Henrik, Cao, Yihai, Griffioen, Arjan W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587443/
https://www.ncbi.nlm.nih.gov/pubmed/30101525
http://dx.doi.org/10.1002/path.5152

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