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Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system
Finasteride 1 mg is considered to be the standard treatment method for male androgenetic alopecia (AGA). However, there have only been a few studies investigating its long‐term efficacy. Moreover, its effect on various types of AGA remains unknown. In this study, the authors investigated the 5‐year...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587453/ https://www.ncbi.nlm.nih.gov/pubmed/30536893 http://dx.doi.org/10.1111/1346-8138.14719 |
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author | Shin, Jung‐Won Chung, Euy‐Hyun Kim, Moon‐Bum Kim, Tae‐Ook Kim, Woo‐Il Huh, Chang‐Hun |
author_facet | Shin, Jung‐Won Chung, Euy‐Hyun Kim, Moon‐Bum Kim, Tae‐Ook Kim, Woo‐Il Huh, Chang‐Hun |
author_sort | Shin, Jung‐Won |
collection | PubMed |
description | Finasteride 1 mg is considered to be the standard treatment method for male androgenetic alopecia (AGA). However, there have only been a few studies investigating its long‐term efficacy. Moreover, its effect on various types of AGA remains unknown. In this study, the authors investigated the 5‐year efficacy of finasteride 1 mg in Korean men with AGA and analyzed the changes in hair growth according to the distribution of hair loss. The medical records of male AGA patients who were treated with oral finasteride for a period of at least 5 years at two university hospitals were retrospectively reviewed. Patients' photographs were evaluated using the basic and specific (BASP) classification and investigator's global assessment. Of the total 126 patients, 108 (85.7%) showed improvement after 5 years of treatment. According to the BASP classification, hair loss of the anterior hair line (basic type), vertex (V type), and frontal area (F type) was improved in 44.4%, 89.7% and 61.2% of patients, respectively. The V type showed a more rapid and steady improvement compared with the other types. Progression of alopecia after peak improvement was seen in 10.3% of cases of the V type, 16.2% of the F type and 0% of the basic type. In conclusion, finasteride 1 mg showed a sustainable effect for at least 5 years in Korean male AGA patients. The exact time points showing signs of first clinical improvement and sustainability were different depending on the type of alopecia. |
format | Online Article Text |
id | pubmed-6587453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-65874532019-07-02 Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system Shin, Jung‐Won Chung, Euy‐Hyun Kim, Moon‐Bum Kim, Tae‐Ook Kim, Woo‐Il Huh, Chang‐Hun J Dermatol Original Articles Finasteride 1 mg is considered to be the standard treatment method for male androgenetic alopecia (AGA). However, there have only been a few studies investigating its long‐term efficacy. Moreover, its effect on various types of AGA remains unknown. In this study, the authors investigated the 5‐year efficacy of finasteride 1 mg in Korean men with AGA and analyzed the changes in hair growth according to the distribution of hair loss. The medical records of male AGA patients who were treated with oral finasteride for a period of at least 5 years at two university hospitals were retrospectively reviewed. Patients' photographs were evaluated using the basic and specific (BASP) classification and investigator's global assessment. Of the total 126 patients, 108 (85.7%) showed improvement after 5 years of treatment. According to the BASP classification, hair loss of the anterior hair line (basic type), vertex (V type), and frontal area (F type) was improved in 44.4%, 89.7% and 61.2% of patients, respectively. The V type showed a more rapid and steady improvement compared with the other types. Progression of alopecia after peak improvement was seen in 10.3% of cases of the V type, 16.2% of the F type and 0% of the basic type. In conclusion, finasteride 1 mg showed a sustainable effect for at least 5 years in Korean male AGA patients. The exact time points showing signs of first clinical improvement and sustainability were different depending on the type of alopecia. John Wiley and Sons Inc. 2018-12-07 2019-02 /pmc/articles/PMC6587453/ /pubmed/30536893 http://dx.doi.org/10.1111/1346-8138.14719 Text en © 2018 The Authors. The Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Japanese Dermatological Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Shin, Jung‐Won Chung, Euy‐Hyun Kim, Moon‐Bum Kim, Tae‐Ook Kim, Woo‐Il Huh, Chang‐Hun Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system |
title | Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system |
title_full | Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system |
title_fullStr | Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system |
title_full_unstemmed | Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system |
title_short | Evaluation of long‐term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system |
title_sort | evaluation of long‐term efficacy of finasteride in korean men with androgenetic alopecia using the basic and specific classification system |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587453/ https://www.ncbi.nlm.nih.gov/pubmed/30536893 http://dx.doi.org/10.1111/1346-8138.14719 |
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