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Loss of the GPI‐anchor in B‐lymphoblastic leukemia by epigenetic downregulation of PIGH expression

Adult B‐lymphoblastic leukemia (B‐ALL) is a hematological malignancy characterized by genetic heterogeneity. Despite successful remission induction with classical chemotherapeutics and novel targeted agents, enduring remission is often hampered by disease relapse due to outgrowth of a pre‐existing s...

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Detalles Bibliográficos
Autores principales: Loeff, Floris C., Rijs, Kevin, van Egmond, Esther H. M., Zoutman, Willem H., Qiao, Xiaohang, Kroes, Wilhelmina G. M., Veld, Sabrina A. J., Griffioen, Marieke, Vermeer, Maarten H., Neefjes, Jacques, Frederik Falkenburg, J. H., Halkes, Constantijn J. M., Jedema, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587464/
https://www.ncbi.nlm.nih.gov/pubmed/30370942
http://dx.doi.org/10.1002/ajh.25337