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Loss of the GPI‐anchor in B‐lymphoblastic leukemia by epigenetic downregulation of PIGH expression
Adult B‐lymphoblastic leukemia (B‐ALL) is a hematological malignancy characterized by genetic heterogeneity. Despite successful remission induction with classical chemotherapeutics and novel targeted agents, enduring remission is often hampered by disease relapse due to outgrowth of a pre‐existing s...
Autores principales: | Loeff, Floris C., Rijs, Kevin, van Egmond, Esther H. M., Zoutman, Willem H., Qiao, Xiaohang, Kroes, Wilhelmina G. M., Veld, Sabrina A. J., Griffioen, Marieke, Vermeer, Maarten H., Neefjes, Jacques, Frederik Falkenburg, J. H., Halkes, Constantijn J. M., Jedema, Inge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587464/ https://www.ncbi.nlm.nih.gov/pubmed/30370942 http://dx.doi.org/10.1002/ajh.25337 |
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