The effect of Activin‐A on periodontal ligament fibroblasts‐mediated osteoclast formation in healthy donors and in patients with fibrodysplasia ossificans progressiva

Fibrodysplasia ossificans progressiva (FOP) is a genetic disease characterized by heterotopic ossification (HO). The disease is caused by a mutation in the activin receptor type 1 (ACVR1) gene that enhances this receptor's responsiveness to Activin‐A. Binding of Activin‐A to the mutated ACVR1 r...

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Detalles Bibliográficos
Autores principales: Schoenmaker, Ton, Wouters, Fenne, Micha, Dimitra, Forouzanfar, Tim, Netelenbos, Coen, Eekhoff, E. Marelise W., Bravenboer, Nathalie, de Vries, Teun J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587553/
https://www.ncbi.nlm.nih.gov/pubmed/30417373
http://dx.doi.org/10.1002/jcp.27693

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