Whole genome sequencing reveals rare off‐target mutations and considerable inherent genetic or/and somaclonal variations in CRISPR/Cas9‐edited cotton plants

The CRISPR/Cas9 system has been extensively applied for crop improvement. However, our understanding of Cas9 specificity is very limited in Cas9‐edited plants. To identify on‐ and off‐target mutation in an edited crop, we described whole genome sequencing (WGS) of 14 Cas9‐edited cotton plants target...

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Detalles Bibliográficos
Autores principales: Li, Jianying, Manghwar, Hakim, Sun, Lin, Wang, Pengcheng, Wang, Guanying, Sheng, Hanyan, Zhang, Jie, Liu, Hao, Qin, Lei, Rui, Hangping, Li, Bo, Lindsey, Keith, Daniell, Henry, Jin, Shuangxia, Zhang, Xianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587709/
https://www.ncbi.nlm.nih.gov/pubmed/30291759
http://dx.doi.org/10.1111/pbi.13020

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