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EMF exposure variation among MRI sequences from pediatric examination protocols

The magnetic resonance imaging (MRI) exposure environment is unique due to the mixture and intensity of magnetic fields involved. Current safety regulations are based on well‐known acute effects of heating and neuroexcitation while the scientific grounds for possible long‐term effects from MRI expos...

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Autores principales: Frankel, Jennifer, Hansson Mild, Kjell, Olsrud, Johan, Wilén, Jonna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587721/
https://www.ncbi.nlm.nih.gov/pubmed/30500987
http://dx.doi.org/10.1002/bem.22159
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author Frankel, Jennifer
Hansson Mild, Kjell
Olsrud, Johan
Wilén, Jonna
author_facet Frankel, Jennifer
Hansson Mild, Kjell
Olsrud, Johan
Wilén, Jonna
author_sort Frankel, Jennifer
collection PubMed
description The magnetic resonance imaging (MRI) exposure environment is unique due to the mixture and intensity of magnetic fields involved. Current safety regulations are based on well‐known acute effects of heating and neuroexcitation while the scientific grounds for possible long‐term effects from MRI exposure are lacking. Epidemiological research requires careful exposure characterization, and as a first step toward improved exposure assessment we set out to characterize the MRI‐patient exposure environment. Seven MRI sequences were run on a 3‐Tesla scanner while the radiofrequency and gradient magnetic fields were measured inside the scanner bore. The sequences were compared in terms of 14 different exposure parameters. To study within–sequence variability, we varied sequence settings such as flip angle and slice thickness one at a time, to determine if they had any impact on exposure endpoints. There were significant differences between two or more sequences for all fourteen exposure parameters. Within–sequence differences were up to 60% of the corresponding between‐sequence differences, and a 5–8 fold exposure increase was caused by variations in flip angle, slice spacing, and field of view. MRI exposure is therefore not only sequence‐specific but also patient‐ and examination occurrence‐specific, a complexity that requires careful consideration for an MRI exposure assessment in epidemiological studies to be meaningful. Bioelectromagnetics. 40:3–15, 2019. © 2018 The Authors. Bioelectromagnetics Published by Wiley Periodicals, Inc.
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spelling pubmed-65877212019-07-02 EMF exposure variation among MRI sequences from pediatric examination protocols Frankel, Jennifer Hansson Mild, Kjell Olsrud, Johan Wilén, Jonna Bioelectromagnetics Research Articles The magnetic resonance imaging (MRI) exposure environment is unique due to the mixture and intensity of magnetic fields involved. Current safety regulations are based on well‐known acute effects of heating and neuroexcitation while the scientific grounds for possible long‐term effects from MRI exposure are lacking. Epidemiological research requires careful exposure characterization, and as a first step toward improved exposure assessment we set out to characterize the MRI‐patient exposure environment. Seven MRI sequences were run on a 3‐Tesla scanner while the radiofrequency and gradient magnetic fields were measured inside the scanner bore. The sequences were compared in terms of 14 different exposure parameters. To study within–sequence variability, we varied sequence settings such as flip angle and slice thickness one at a time, to determine if they had any impact on exposure endpoints. There were significant differences between two or more sequences for all fourteen exposure parameters. Within–sequence differences were up to 60% of the corresponding between‐sequence differences, and a 5–8 fold exposure increase was caused by variations in flip angle, slice spacing, and field of view. MRI exposure is therefore not only sequence‐specific but also patient‐ and examination occurrence‐specific, a complexity that requires careful consideration for an MRI exposure assessment in epidemiological studies to be meaningful. Bioelectromagnetics. 40:3–15, 2019. © 2018 The Authors. Bioelectromagnetics Published by Wiley Periodicals, Inc. John Wiley and Sons Inc. 2018-11-30 2019-01 /pmc/articles/PMC6587721/ /pubmed/30500987 http://dx.doi.org/10.1002/bem.22159 Text en © 2018 The Authors. Bioelectromagnetics Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Frankel, Jennifer
Hansson Mild, Kjell
Olsrud, Johan
Wilén, Jonna
EMF exposure variation among MRI sequences from pediatric examination protocols
title EMF exposure variation among MRI sequences from pediatric examination protocols
title_full EMF exposure variation among MRI sequences from pediatric examination protocols
title_fullStr EMF exposure variation among MRI sequences from pediatric examination protocols
title_full_unstemmed EMF exposure variation among MRI sequences from pediatric examination protocols
title_short EMF exposure variation among MRI sequences from pediatric examination protocols
title_sort emf exposure variation among mri sequences from pediatric examination protocols
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587721/
https://www.ncbi.nlm.nih.gov/pubmed/30500987
http://dx.doi.org/10.1002/bem.22159
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