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Lysyl oxidase‐like 2 is a regulator of angiogenesis through modulation of endothelial‐to‐mesenchymal transition

Lysyl oxidase‐like 2 (LOXL2) belongs to the family of lysyl oxidases, and as such promotes crosslinking of collagens and elastin by oxidative deamination of lysine residues. In endothelial cells (ECs), LOXL2 is involved in crosslinking and scaffolding of collagen IV. Additionally, several reports ha...

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Detalles Bibliográficos
Autores principales: de Jong, Olivier G., van der Waals, Lizet M., Kools, Farah R. W., Verhaar, Marianne C., van Balkom, Bas W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587725/
https://www.ncbi.nlm.nih.gov/pubmed/30387148
http://dx.doi.org/10.1002/jcp.27695