Eosinophilia and reduced STAT3 signaling affect neutrophil cell death in autosomal‐dominant Hyper‐IgE syndrome

The autosomal‐dominant hyper‐IgE syndrome (HIES), caused by mutations in STAT3, is a rare primary immunodeficiency that predisposes to mucocutaneous candidiasis and staphylococcal skin and lung infections. This infection phenotype is suggestive of defects in neutrophils, but data on neutrophil funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Farmand, Susan, Kremer, Bernhard, Häffner, Monika, Pütsep, Katrin, Bergman, Peter, Sundin, Mikael, Ritterbusch, Henrike, Seidl, Maximilian, Follo, Marie, Henneke, Philipp, Henriques‐Normark, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Immunity to infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587726/
https://www.ncbi.nlm.nih.gov/pubmed/30315710
http://dx.doi.org/10.1002/eji.201847650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587726/
https://www.ncbi.nlm.nih.gov/pubmed/30315710
http://dx.doi.org/10.1002/eji.201847650

Ejemplares similares