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Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication

INTRODUCTION: To objectively quantify patients' physical activity and analyze the relationships between physical activity levels, psychopathology, and sedative medication in acute hospital dementia care. MATERIALS AND METHODS: In this cross‐sectional study, we assessed the patients' physic...

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Autores principales: Fleiner, Tim, Gersie, Marleen, Ghosh, Sayantan, Mellone, Sabato, Zijlstra, Wiebren, Haussermann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587796/
https://www.ncbi.nlm.nih.gov/pubmed/30403307
http://dx.doi.org/10.1002/gps.5021
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author Fleiner, Tim
Gersie, Marleen
Ghosh, Sayantan
Mellone, Sabato
Zijlstra, Wiebren
Haussermann, Peter
author_facet Fleiner, Tim
Gersie, Marleen
Ghosh, Sayantan
Mellone, Sabato
Zijlstra, Wiebren
Haussermann, Peter
author_sort Fleiner, Tim
collection PubMed
description INTRODUCTION: To objectively quantify patients' physical activity and analyze the relationships between physical activity levels, psychopathology, and sedative medication in acute hospital dementia care. MATERIALS AND METHODS: In this cross‐sectional study, we assessed the patients' physical activity based on data collection by hybrid motion sensors attached on their lower back. Daily doses of antipsychotics have been converted to olanzapine‐equivalents and daily benzodiazepine medication is reported as diazepam‐equivalents. We assessed patients' neuropsychiatric symptoms with the Neuropsychiatric Inventory and the Cohen‐Mansfield Agitation Inventory. RESULTS: We analyzed motion sensor data from 64 patients (MMSE M = 18.6). On average, patients were lying for 11.5 hours, sitting/standing sedentary for 10.3 hours, sitting/standing active for 1.0 hours, and walking for 1.2 hours per day. The analysis revealed no correlations between patients' physical activity and antipsychotic or benzodiazepine medication. More severe neuropsychiatric symptoms were associated with a decrease in the patients' physical activity (r = .32, P = .01). In particular, patients with apathy symptoms were less physically active than patients without apathy symptoms. DISCUSSION: The results reveal that most of the patients in acute dementia care had very low levels of physical activity. Their physical inactivity may be due to the severity of their neuropsychiatric symptoms, especially apathy. Antipsychotic and benzodiazepine medication appeared to have less impact on patients' physical activity. Dementia care should pay more attention to prevent physical inactivity in patients.
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spelling pubmed-65877962019-07-02 Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication Fleiner, Tim Gersie, Marleen Ghosh, Sayantan Mellone, Sabato Zijlstra, Wiebren Haussermann, Peter Int J Geriatr Psychiatry Research Articles INTRODUCTION: To objectively quantify patients' physical activity and analyze the relationships between physical activity levels, psychopathology, and sedative medication in acute hospital dementia care. MATERIALS AND METHODS: In this cross‐sectional study, we assessed the patients' physical activity based on data collection by hybrid motion sensors attached on their lower back. Daily doses of antipsychotics have been converted to olanzapine‐equivalents and daily benzodiazepine medication is reported as diazepam‐equivalents. We assessed patients' neuropsychiatric symptoms with the Neuropsychiatric Inventory and the Cohen‐Mansfield Agitation Inventory. RESULTS: We analyzed motion sensor data from 64 patients (MMSE M = 18.6). On average, patients were lying for 11.5 hours, sitting/standing sedentary for 10.3 hours, sitting/standing active for 1.0 hours, and walking for 1.2 hours per day. The analysis revealed no correlations between patients' physical activity and antipsychotic or benzodiazepine medication. More severe neuropsychiatric symptoms were associated with a decrease in the patients' physical activity (r = .32, P = .01). In particular, patients with apathy symptoms were less physically active than patients without apathy symptoms. DISCUSSION: The results reveal that most of the patients in acute dementia care had very low levels of physical activity. Their physical inactivity may be due to the severity of their neuropsychiatric symptoms, especially apathy. Antipsychotic and benzodiazepine medication appeared to have less impact on patients' physical activity. Dementia care should pay more attention to prevent physical inactivity in patients. John Wiley and Sons Inc. 2018-11-27 2019-02 /pmc/articles/PMC6587796/ /pubmed/30403307 http://dx.doi.org/10.1002/gps.5021 Text en © 2018 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Research Articles
Fleiner, Tim
Gersie, Marleen
Ghosh, Sayantan
Mellone, Sabato
Zijlstra, Wiebren
Haussermann, Peter
Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication
title Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication
title_full Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication
title_fullStr Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication
title_full_unstemmed Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication
title_short Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication
title_sort prominent physical inactivity in acute dementia care: psychopathology seems to be more important than the dose of sedative medication
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587796/
https://www.ncbi.nlm.nih.gov/pubmed/30403307
http://dx.doi.org/10.1002/gps.5021
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