Glucose levels and diabetes are not associated with the risk of venous thrombosis: results from the MEGA case‐control study

It is unclear whether hyperglycaemia or diabetes mellitus are risk factors for a first venous thrombosis (VT). Self‐reported diabetes status and fasting glucose (FG) measures were collected from the Multiple Environmental and Genetic Assessment (MEGA) study to confirm these associations. FG levels w...

Descripción completa

Detalles Bibliográficos
Autores principales: Li‐Gao, Ruifang, Morelli, Vânia M., Lijfering, Willem M., Cannegieter, Suzanne C., Rosendaal, Frits R., van Hylckama Vlieg, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Platelets, Haemostasis and Thrombosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587875/
https://www.ncbi.nlm.nih.gov/pubmed/30478992
http://dx.doi.org/10.1111/bjh.15599
Descripción
Sumario:It is unclear whether hyperglycaemia or diabetes mellitus are risk factors for a first venous thrombosis (VT). Self‐reported diabetes status and fasting glucose (FG) measures were collected from the Multiple Environmental and Genetic Assessment (MEGA) study to confirm these associations. FG levels were categorized based on the World Health Organization criteria [<6·1 (reference), 6·1–7·0 (2nd), ≥7·0 (3rd) mmol/l]. Logistic regression was performed to quantify the associations. Neither increased FG levels [Odds ratio (95% confidence interval): 0·98 (0·69–1·37) 2nd vs. reference, 0·97 (0·58–1·63) 3rd vs. reference] nor self‐reported diabetes [1·12 (0·80–1·58)] were associated with an increased risk of a first VT.

Ejemplares similares