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Anti-complement Treatment for Paroxysmal Nocturnal Hemoglobinuria: Time for Proximal Complement Inhibition? A Position Paper From the SAAWP of the EBMT
The treatment of paroxysmal nocturnal hemoglobinuria has been revolutionized by the introduction of the anti-C5 agent eculizumab; however, eculizumab is not the cure for Paroxysmal nocturnal hemoglobinuria (PNH), and room for improvement remains. Indeed, the hematological benefit during eculizumab t...
Autores principales: | Risitano, Antonio M., Marotta, Serena, Ricci, Patrizia, Marano, Luana, Frieri, Camilla, Cacace, Fabiana, Sica, Michela, Kulasekararaj, Austin, Calado, Rodrigo T., Scheinberg, Phillip, Notaro, Rosario, Peffault de Latour, Regis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587878/ https://www.ncbi.nlm.nih.gov/pubmed/31258525 http://dx.doi.org/10.3389/fimmu.2019.01157 |
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