Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients

Adipose mesenchymal stem cells (ASC) are considered minimally immunogenic. This is due to the low expression of human leukocyte antigens I (HLA-I), lack of HLA-II expression and low expression of co-stimulatory molecules such as CD40 and CD80. The low rate of observed immunological rejection as well...

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Detalles Bibliográficos
Autores principales: Avivar-Valderas, Alvaro, Martín-Martín, Cristina, Ramírez, Cristina, Del Río, Borja, Menta, Ramón, Mancheño-Corvo, Pablo, Ortiz-Virumbrales, Maitane, Herrero-Méndez, Ángel, Panés, Julián, García-Olmo, Damián, Castañer, José Luís, Palacios, Itziar, Lombardo, Eleuterio, Dalemans, Wilfried, DelaRosa, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587893/
https://www.ncbi.nlm.nih.gov/pubmed/31258526
http://dx.doi.org/10.3389/fimmu.2019.01244

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