Expression of STAT3-regulated genes in circulating CD4+ T cells discriminates rheumatoid arthritis independently of clinical parameters in early arthritis

OBJECTIVES: Dysregulated signal transduction and activator of transcription-3 (STAT3) signalling in CD4+ T cells has been proposed as an early pathophysiological event in RA. We sought further evidence for this observation, and to determine its clinical relevance. METHODS: Microarray technology was...

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Detalles Bibliográficos
Autores principales: Anderson, Amy E, Maney, Nicola J, Nair, Nisha, Lendrem, Dennis W, Skelton, Andrew J, Diboll, Julie, Brown, Philip M, Smith, Graham R, Carmody, Ruaidhrí J, Barton, Anne, Isaacs, John D, Pratt, Arthur G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587924/
https://www.ncbi.nlm.nih.gov/pubmed/30753680
http://dx.doi.org/10.1093/rheumatology/kez003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587924/
https://www.ncbi.nlm.nih.gov/pubmed/30753680
http://dx.doi.org/10.1093/rheumatology/kez003

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