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Pharmacokinetics and ex vivo anti‐inflammatory effects of oral misoprostol in horses

BACKGROUND: Misoprostol is an E prostanoid (EP) 2, 3 and 4 receptor agonist that is anecdotally used to treat and prevent NSAID‐induced GI injury in horses. Misoprostol elicits anti‐inflammatory effects in vivo in men and rodents, and inhibits TNFα production in equine leucocytes in vitro. OBJECTIVE...

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Detalles Bibliográficos
Autores principales:	Martin, E. M., Schirmer, J. M., Jones, S. L., Davis, J. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Experimental and Basic Research Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587934/ https://www.ncbi.nlm.nih.gov/pubmed/30256450 http://dx.doi.org/10.1111/evj.13024

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