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Evaluating guselkumab: an anti-IL-23 antibody for the treatment of plaque psoriasis

The approval of guselkumab marks the entry of the IL-23 inhibitor class into the therapeutic armamentarium for patients with moderate-to-severe plaque psoriasis. This class specifically targets the upstream portion of the type 17 helper T (Th17) axis, which has been implicated as a key driver of the...

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Detalles Bibliográficos
Autores principales: Yang, Eric J, Smith, Mary Patricia, Ly, Karen, Bhutani, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587972/
https://www.ncbi.nlm.nih.gov/pubmed/31354244
http://dx.doi.org/10.2147/DDDT.S137588