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Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer

KRAS mutation is a well‐known marker for poor response to targeted treatment and patient prognosis in microsatellite stable (MSS) colorectal cancer (CRC). However, variation in clinical outcomes among patients wild‐type for KRAS underlines that this is not a homogeneous population. Here, we evaluate...

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Detalles Bibliográficos
Autores principales: Eilertsen, Ina A., Sveen, Anita, Strømme, Jonas M., Skotheim, Rolf I., Nesbakken, Arild, Lothe, Ragnhild A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587976/
https://www.ncbi.nlm.nih.gov/pubmed/30121958
http://dx.doi.org/10.1002/ijc.31809

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