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Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study

OBJECTIVES: The purpose of this study was to examine the association of prepubertal body mass index (BMI) and weight status with pubertal development in boys and girls in Chongqing, China. METHODS: In a longitudinal study, 1237 students (695 boys and 542 girls) were recruited from Chongqing, China,...

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Autores principales: Li, Wenyan, Liu, Qin, Deng, Xu, Chen, Yiwen, Yang, Bo, Huang, Xin, Østbye, Truls
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587982/
https://www.ncbi.nlm.nih.gov/pubmed/30387539
http://dx.doi.org/10.1002/ajhb.23195
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author Li, Wenyan
Liu, Qin
Deng, Xu
Chen, Yiwen
Yang, Bo
Huang, Xin
Østbye, Truls
author_facet Li, Wenyan
Liu, Qin
Deng, Xu
Chen, Yiwen
Yang, Bo
Huang, Xin
Østbye, Truls
author_sort Li, Wenyan
collection PubMed
description OBJECTIVES: The purpose of this study was to examine the association of prepubertal body mass index (BMI) and weight status with pubertal development in boys and girls in Chongqing, China. METHODS: In a longitudinal study, 1237 students (695 boys and 542 girls) were recruited from Chongqing, China, and examined at baseline, then followed every 6 months for three and a half years. Height, weight, testicular volume, and breast development were measured at every examination. Age of first spermatorrhea and menarche were obtained from self‐report. Subjects were divided into normal weight, overweight, and obese groups according to baseline BMI. Multivariable Cox regression analysis was used to examine the association of BMI and weight status with pubertal development. RESULTS: In girls, higher prepubertal BMI increased the chance of earlier menarche (hazards ratio (HR): 1.205, 95% confidence interval (95% CI): 1.151‐2.261) and breast development (HR: 1.092, 95% CI: 1.045‐1.142). Girls in the overweight (HR: 2.605, 95% CI: 1.716‐3.956) and obese (HR: 2.565, 95% CI: 1.603‐4.103) groups had an increased risk of early menarche compared with those in the normal weight group, while only overweight was associated with an increased risk for earlier breast development (HR: 1.469, 95% CI: 1.024‐2.108). In boys, higher prepubertal BMI was significantly associated with the timing of first spermatorrhea (HR: 1.054, 95% CI: 1.004‐1.106) and testicular development (HR: 1.098, 95% CI: 1.063‐1.135). Overweight (HR: 1.672, 95% CI: 1.204‐2.322) and obesity (HR: 1.598, 95% CI: 1.135‐2.249) increased the hazard of earlier testicular development compared with the normal weight group, while no significant differences were detected among the three weight groups in terms of time to first spermatorrhea. CONCLUSIONS: Higher prepubertal BMI was associated with earlier puberty in both Chinese boys and girls.
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spelling pubmed-65879822019-07-02 Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study Li, Wenyan Liu, Qin Deng, Xu Chen, Yiwen Yang, Bo Huang, Xin Østbye, Truls Am J Hum Biol Original Research Articles OBJECTIVES: The purpose of this study was to examine the association of prepubertal body mass index (BMI) and weight status with pubertal development in boys and girls in Chongqing, China. METHODS: In a longitudinal study, 1237 students (695 boys and 542 girls) were recruited from Chongqing, China, and examined at baseline, then followed every 6 months for three and a half years. Height, weight, testicular volume, and breast development were measured at every examination. Age of first spermatorrhea and menarche were obtained from self‐report. Subjects were divided into normal weight, overweight, and obese groups according to baseline BMI. Multivariable Cox regression analysis was used to examine the association of BMI and weight status with pubertal development. RESULTS: In girls, higher prepubertal BMI increased the chance of earlier menarche (hazards ratio (HR): 1.205, 95% confidence interval (95% CI): 1.151‐2.261) and breast development (HR: 1.092, 95% CI: 1.045‐1.142). Girls in the overweight (HR: 2.605, 95% CI: 1.716‐3.956) and obese (HR: 2.565, 95% CI: 1.603‐4.103) groups had an increased risk of early menarche compared with those in the normal weight group, while only overweight was associated with an increased risk for earlier breast development (HR: 1.469, 95% CI: 1.024‐2.108). In boys, higher prepubertal BMI was significantly associated with the timing of first spermatorrhea (HR: 1.054, 95% CI: 1.004‐1.106) and testicular development (HR: 1.098, 95% CI: 1.063‐1.135). Overweight (HR: 1.672, 95% CI: 1.204‐2.322) and obesity (HR: 1.598, 95% CI: 1.135‐2.249) increased the hazard of earlier testicular development compared with the normal weight group, while no significant differences were detected among the three weight groups in terms of time to first spermatorrhea. CONCLUSIONS: Higher prepubertal BMI was associated with earlier puberty in both Chinese boys and girls. John Wiley & Sons, Inc. 2018-11-02 2018 /pmc/articles/PMC6587982/ /pubmed/30387539 http://dx.doi.org/10.1002/ajhb.23195 Text en © 2018 The Authors. American Journal of Human Biology published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Articles
Li, Wenyan
Liu, Qin
Deng, Xu
Chen, Yiwen
Yang, Bo
Huang, Xin
Østbye, Truls
Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study
title Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study
title_full Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study
title_fullStr Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study
title_full_unstemmed Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study
title_short Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study
title_sort association of prepubertal obesity with pubertal development in chinese girls and boys: a longitudinal study
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587982/
https://www.ncbi.nlm.nih.gov/pubmed/30387539
http://dx.doi.org/10.1002/ajhb.23195
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