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P in the right place: Revisiting the evidential value of P‐values

P‐values are often calculated when testing hypotheses in quantitative settings, and low P‐values are typically used as evidential measures to support research findings in published medical research. This article reviews old and new arguments questioning the evidential value of P‐values. Critiques of...

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Detalles Bibliográficos
Autor principal: Lytsy, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587984/
https://www.ncbi.nlm.nih.gov/pubmed/30398018
http://dx.doi.org/10.1111/jebm.12319
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author Lytsy, Per
author_facet Lytsy, Per
author_sort Lytsy, Per
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description P‐values are often calculated when testing hypotheses in quantitative settings, and low P‐values are typically used as evidential measures to support research findings in published medical research. This article reviews old and new arguments questioning the evidential value of P‐values. Critiques of the P‐value include that it is confounded, fickle, and overestimates the evidence against the null. P‐values may turn out falsely low in studies due to random or systematic errors. Even correctly low P‐values do not logically provide support to any hypothesis. Recent studies show low replication rates of significant findings, questioning the dependability of published low P‐values. P‐values are poor indicators in support of scientific propositions. P‐values must be inferred by a thorough understanding of the study's question, design, and conduct. Null hypothesis significance testing will likely remain an important method in quantitative analysis but may be complemented with other statistical techniques that more straightforwardly address the size and precision of an effect or the plausibility that a hypothesis is true.
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spelling pubmed-65879842019-07-02 P in the right place: Revisiting the evidential value of P‐values Lytsy, Per J Evid Based Med Methodology P‐values are often calculated when testing hypotheses in quantitative settings, and low P‐values are typically used as evidential measures to support research findings in published medical research. This article reviews old and new arguments questioning the evidential value of P‐values. Critiques of the P‐value include that it is confounded, fickle, and overestimates the evidence against the null. P‐values may turn out falsely low in studies due to random or systematic errors. Even correctly low P‐values do not logically provide support to any hypothesis. Recent studies show low replication rates of significant findings, questioning the dependability of published low P‐values. P‐values are poor indicators in support of scientific propositions. P‐values must be inferred by a thorough understanding of the study's question, design, and conduct. Null hypothesis significance testing will likely remain an important method in quantitative analysis but may be complemented with other statistical techniques that more straightforwardly address the size and precision of an effect or the plausibility that a hypothesis is true. John Wiley and Sons Inc. 2018-11-05 2018-11 /pmc/articles/PMC6587984/ /pubmed/30398018 http://dx.doi.org/10.1111/jebm.12319 Text en © 2018 The Authors Journal of Evidence-Based Medicine published by Chinese Cochrane Center, West China Hospital of Sichuan University and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Methodology
Lytsy, Per
P in the right place: Revisiting the evidential value of P‐values
title P in the right place: Revisiting the evidential value of P‐values
title_full P in the right place: Revisiting the evidential value of P‐values
title_fullStr P in the right place: Revisiting the evidential value of P‐values
title_full_unstemmed P in the right place: Revisiting the evidential value of P‐values
title_short P in the right place: Revisiting the evidential value of P‐values
title_sort p in the right place: revisiting the evidential value of p‐values
topic Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587984/
https://www.ncbi.nlm.nih.gov/pubmed/30398018
http://dx.doi.org/10.1111/jebm.12319
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