Preclinical and Clinical Evidence for a Distinct Regulation of Mu Opioid and Type 1 Cannabinoid Receptor Genes Expression in Obesity

Among endogenous signaling networks involved in both rewarding and homeostatic mechanisms of obesity, a relevant role is played by the endocannabinoid (ECS) and the opioid (EOS) systems. We here studied the transcriptional regulation of ECS and EOS genes in the hypothalamus of Diet-induced obesity r...

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Detalles Bibliográficos
Autores principales: Pucci, Mariangela, Micioni Di Bonaventura, Maria Vittoria, Vezzoli, Valeria, Zaplatic, Elizabeta, Massimini, Marcella, Mai, Stefania, Sartorio, Alessandro, Scacchi, Massimo, Persani, Luca, Maccarrone, Mauro, Cifani, Carlo, D’Addario, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588048/
https://www.ncbi.nlm.nih.gov/pubmed/31258545
http://dx.doi.org/10.3389/fgene.2019.00523

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