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Withaferin A inhibits adipogenesis in 3T3-F442A cell line, improves insulin sensitivity and promotes weight loss in high fat diet-induced obese mice
The increased prevalence of obesity and associated insulin resistance calls for effective therapeutic treatment of metabolic diseases. The current PPARγ-targeting antidiabetic drugs have undesirable side effects. The present study investigated the anti-diabetic and anti-obesity effects of withaferin...
Autores principales: | Khalilpourfarshbafi, Manizheh, Devi Murugan, Dharmani, Abdul Sattar, Munavvar Zubaid, Sucedaram, Yamuna, Abdullah, Nor Azizan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588247/ https://www.ncbi.nlm.nih.gov/pubmed/31226166 http://dx.doi.org/10.1371/journal.pone.0218792 |
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