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L3MBTL1 Regulates ALS/FTD-associated Proteotoxicity and Quality Control

Misfolded protein toxicity and failure of protein quality control underlie neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Here, we identified Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) as a previously unknown regulator of prot...

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Detalles Bibliográficos
Autores principales:	Lu, Jiayin, Periz, Goran, Lu, Yu-Ning, Tang, Qing, Liu, Yang, Zhang, Tao, Shah, Yajas, Thombre, Ravi, Aljumaah, Reham, Li, Weixin, Mojsilovic-Petrovic, Jelena, Ji, Yon, Johnson, Kenji, Kalb, Robert, Wang, Jiou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588399/ https://www.ncbi.nlm.nih.gov/pubmed/31061493 http://dx.doi.org/10.1038/s41593-019-0384-5

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