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Molecular architecture, polar targeting and biogenesis of the Legionella Dot/Icm T4SS

Legionella pneumophila survives and replicates inside host cells by secreting ~300 effectors through the Dot/Icm type IVB secretion system (T4BSS). Here, we used complementary electron cryotomography (ECT) and immunofluorescence microscopy (IF) to investigate the molecular architecture and biogenesi...

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Detalles Bibliográficos
Autores principales: Ghosal, Debnath, Jeong, KwangCheol C., Chang, Yi-Wei, Gyore, Jacob, Teng, Lin, Gardner, Adam, Vogel, Joseph P., Jensen, Grant J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588468/
https://www.ncbi.nlm.nih.gov/pubmed/31011165
http://dx.doi.org/10.1038/s41564-019-0427-4