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Viral complementation of immunodeficiency confers protection against enteric pathogens via IFN-λ

Commensal microbes profoundly impact host immunity to enteric viral infections(1). We have shown that the bacterial microbiota and host antiviral cytokine interferon-lambda (IFN-λ) determine the persistence of murine norovirus in the gut(2,3). However, the effects of the virome in modulating enteric...

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Detalles Bibliográficos
Autores principales: Ingle, Harshad, Lee, Sanghyun, Ai, Teresa, Orvedahl, Anthony, Rodgers, Rachel, Zhao, Guoyan, Sullender, Meagan, Peterson, Stefan T., Locke, Marissa, Liu, Ta-Chiang, Yokoyama, Christine C., Sharp, Bridgett, Schultz-Cherry, Stacey, Miner, Jonathan J., Baldridge, Megan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588490/
https://www.ncbi.nlm.nih.gov/pubmed/30936486
http://dx.doi.org/10.1038/s41564-019-0416-7