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Identification of HIV transmitting CD11c(+) human epidermal dendritic cells
Langerhans cells (LC) are thought to be the only mononuclear phagocyte population in the epidermis where they detect pathogens. Here, we show that CD11c(+) dendritic cells (DCs) are also present. These cells are transcriptionally similar to dermal cDC2 but are more efficient antigen-presenting cells...
Autores principales: | Bertram, Kirstie M., Botting, Rachel A., Baharlou, Heeva, Rhodes, Jake W., Rana, Hafsa, Graham, J. Dinny, Patrick, Ellis, Fletcher, James, Plasto, Toby M., Truong, Naomi R., Royle, Caroline, Doyle, Chloe M., Tong, Orion, Nasr, Najla, Barnouti, Laith, Kohout, Mark P., Brooks, Andrew J., Wines, Michael P., Haertsch, Peter, Lim, Jake, Gosselink, Martijn P., Ctercteko, Grahame, Estes, Jacob D., Churchill, Melissa J., Cameron, Paul U., Hunter, Eric, Haniffa, Muzlifah A., Cunningham, Anthony L., Harman, Andrew N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588576/ https://www.ncbi.nlm.nih.gov/pubmed/31227717 http://dx.doi.org/10.1038/s41467-019-10697-w |
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