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A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons

Neurons created from human induced pluripotent stem cells (hiPSCs) provide the capability of identifying biological mechanisms that underlie brain disorders. IPSC-derived human neurons, or iNs, hold promise for advancing precision medicine through drug screening, though it remains unclear to what ex...

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Detalles Bibliográficos
Autores principales: Sridharan, BanuPriya, Hubbs, Christopher, Llamosas, Nerea, Kilinc, Murat, Singhera, Fakhar U., Willems, Erik, Piper, David R., Scampavia, Louis, Rumbaugh, Gavin, Spicer, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588600/
https://www.ncbi.nlm.nih.gov/pubmed/31227747
http://dx.doi.org/10.1038/s41598-019-45265-1