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A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons
Neurons created from human induced pluripotent stem cells (hiPSCs) provide the capability of identifying biological mechanisms that underlie brain disorders. IPSC-derived human neurons, or iNs, hold promise for advancing precision medicine through drug screening, though it remains unclear to what ex...
Autores principales: | Sridharan, BanuPriya, Hubbs, Christopher, Llamosas, Nerea, Kilinc, Murat, Singhera, Fakhar U., Willems, Erik, Piper, David R., Scampavia, Louis, Rumbaugh, Gavin, Spicer, Timothy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588600/ https://www.ncbi.nlm.nih.gov/pubmed/31227747 http://dx.doi.org/10.1038/s41598-019-45265-1 |
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