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Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo

In this study, we have developed highly expandable neural stem cells (NSCs) from HESCs and iPSCs that artificially express the oligodendrocyte (OL) specific transcription factor gene Zfp488. This is enough to restrict them to an exclusive oligodendrocyte progenitor cell (OPC) fate during differentia...

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Detalles Bibliográficos
Autores principales:	Biswas, Sangita, Chung, Seung Hyuk, Jiang, Peng, Dehghan, Samaneh, Deng, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588721/ https://www.ncbi.nlm.nih.gov/pubmed/31227736 http://dx.doi.org/10.1038/s41598-019-45247-3

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