Cargando…

Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo

In this study, we have developed highly expandable neural stem cells (NSCs) from HESCs and iPSCs that artificially express the oligodendrocyte (OL) specific transcription factor gene Zfp488. This is enough to restrict them to an exclusive oligodendrocyte progenitor cell (OPC) fate during differentia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Biswas, Sangita, Chung, Seung Hyuk, Jiang, Peng, Dehghan, Samaneh, Deng, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588721/ https://www.ncbi.nlm.nih.gov/pubmed/31227736 http://dx.doi.org/10.1038/s41598-019-45247-3

Ejemplares similares

Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro
por: Namchaiw, Poommaree, et al.
Publicado: (2019)

Differentiation of Embryonic Stem Cells into Oligodendrocyte Precursors
por: Jiang, Peng, et al.
Publicado: (2010)

In vitro neural/glial differentiation potential of periodontal ligament stem cells
por: Li, Xiaojie, et al.
Publicado: (2010)

Rationale and Methodology of Reprogramming for Generation of Induced Pluripotent Stem Cells and Induced Neural Progenitor Cells
por: Tian, Zuojun, et al.
Publicado: (2016)

Clobetasol propionate enhances neural stem cell and oligodendrocyte differentiation
por: Shi, Wentao, et al.
Publicado: (2019)

Galectin-3-Mediated Glial Crosstalk Drives Oligodendrocyte Differentiation and (Re)myelination
por: Thomas, Laura, et al.
Publicado: (2018)

Effects of neurotrophin-3 on the differentiation of neural stem cells into neurons and oligodendrocytes
por: Zhu, Guowei, et al.
Publicado: (2012)

PPARγ Agonists Promote Oligodendrocyte Differentiation of Neural Stem Cells by Modulating Stemness and Differentiation Genes
por: Kanakasabai, Saravanan, et al.
Publicado: (2012)

Zfp488 promotes oligodendrocyte differentiation of neural progenitor cells in adult mice after demyelination
por: Soundarapandian, Mangala M., et al.
Publicado: (2011)

Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes
por: Sharma, Krishna Deo, et al.
Publicado: (2022)

Ex Vivo VEGF Delivery by Neural Stem Cells Enhances Proliferation of Glial Progenitors, Angiogenesis, and Tissue Sparing after Spinal Cord Injury
por: Kim, Hyuk Min, et al.
Publicado: (2009)

Differential Deployment of REST and CoREST Promotes Glial Subtype Specification and Oligodendrocyte Lineage Maturation
por: Abrajano, Joseph J., et al.
Publicado: (2009)

Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes
por: Ye, Dou, et al.
Publicado: (2022)

Sequential Differentiation of Embryonic Stem Cells into Neural Epithelial-Like Stem Cells and Oligodendrocyte Progenitor Cells
por: Bian, Jing, et al.
Publicado: (2016)

Secretome Analysis of Human Oligodendrocytes Derived from Neural Stem Cells
por: Kim, Woo Kyung, et al.
Publicado: (2014)

Tmeff2 is expressed in differentiating oligodendrocytes but dispensable for their differentiation in vivo
por: Huang, Hao, et al.
Publicado: (2017)

Generation of in vivo neural stem cells using partially reprogrammed cells defective in in vitro differentiation potential
por: Kim, Jong Soo, et al.
Publicado: (2017)

Glial metabotropic glutamate receptor-4 increases maturation and survival of oligodendrocytes
por: Spampinato, Simona Federica, et al.
Publicado: (2015)

Direct Conversion to Achieve Glial Cell Fates: Oligodendrocytes and Schwann Cells
por: Yun, Wonjin, et al.
Publicado: (2022)

Mesenchymal Stem Cells and Induced Pluripotent Stem Cells as Therapies for Multiple Sclerosis
por: Xiao, Juan, et al.
Publicado: (2015)

Gastrodin blocks neural stem cell differentiation into glial cells mediated by kainic acid★
por: Sun, Guifang, et al.
Publicado: (2012)

Effects of ginsenoside-Rg1 on the proliferation and glial-like directed differentiation of embryonic rat cortical neural stem cells in vitro
por: Gao, Jian, et al.
Publicado: (2017)

Function of B-Cell CLL/Lymphoma 11B in Glial Progenitor Proliferation and Oligodendrocyte Maturation
por: Wang, Chih-Yen, et al.
Publicado: (2018)

Differentiation and Maturation of Oligodendrocytes in Human Three-Dimensional Neural Cultures
por: Marton, Rebecca M., et al.
Publicado: (2019)

Fingolimod Enhances Oligodendrocyte Differentiation of Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitors
por: Yazdi, Azadeh, et al.
Publicado: (2018)

M177. THE PROTEOME OF OLIGODENDROCYTES DIFFERENTIATED FROM NEURAL STEM CELL DERIVED FROM SCHIZOPHRENIA PATIENTS
por: Teles Rodrigues, Caroline, et al.
Publicado: (2020)

Assessment of Immunological Potential of Glial Restricted Progenitor Graft In Vivo—Is Immunosuppression Mandatory?
por: Kozlowska, Urszula, et al.
Publicado: (2021)

An Oligodendrocyte Cell Adhesion Molecule at the Site of Assembly of the Paranodal Axo-Glial Junction
por: Tait, Steven, et al.
Publicado: (2000)

Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation
por: Mercer, Tim R, et al.
Publicado: (2010)

Glial Patchwork: Oligodendrocyte Progenitor Cells and Astrocytes Blanket the Central Nervous System
por: Barber, Heather M., et al.
Publicado: (2022)

Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo
por: Fischer, Ulrike, et al.
Publicado: (2015)

Telmisartan Modulates Glial Activation: In Vitro and In Vivo Studies
por: Torika, Nofar, et al.
Publicado: (2016)

Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination
por: Rivera, Francisco J., et al.
Publicado: (2019)

A Novel Vitronectin Peptide Facilitates Differentiation of Oligodendrocytes from Human Pluripotent Stem Cells (Synthetic ECM for Oligodendrocyte Differentiation)
por: Park, Won Ung, et al.
Publicado: (2021)

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells
por: Silva, Maria Elena, et al.
Publicado: (2019)

CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo
por: Dietrich, Joerg, et al.
Publicado: (2006)

Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo
por: Zhu, Yizi, et al.
Publicado: (2022)

In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formation
por: Choi, Hyun Woo, et al.
Publicado: (2017)

Differential Effects of Isoxazole-9 on Neural Stem/Progenitor Cells, Oligodendrocyte Precursor Cells, and Endothelial Progenitor Cells
por: Koh, Seong-Ho, et al.
Publicado: (2015)

In Vitro Expanded Stem Cells from the Developing Retina Fail to Generate Photoreceptors but Differentiate into Myelinating Oligodendrocytes
por: Czekaj, Magdalena, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_cuf5stgsnk0tt2devk5m9bsveo