Lack of the hyaluronan receptor CD44 affects the course of bacterial otitis media and reduces leukocyte recruitment to the middle ear

BACKGROUND: CD44 is a multifunctional molecule that plays major roles in both leukocyte recruitment and tissue proliferation. Since mucosal hyperplasia and leukocyte infiltration of the middle ear cavity are major features of otitis media, we evaluated the role of CD44 in the pathophysiology and cou...

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Detalles Bibliográficos
Autores principales: Lim, Hyun Woo, Pak, Kwang, Kurabi, Arwa, Ryan, Allen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588864/
https://www.ncbi.nlm.nih.gov/pubmed/31226944
http://dx.doi.org/10.1186/s12865-019-0302-3

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