Cargando…

METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

BACKGROUND: METTL3 is known to be involved in all stages in the life cycle of RNA. It affects the tumor formation by the regulation the m6A modification in the mRNAs of critical oncogenes or tumor suppressors. In bladder cancer, METTL3 could promote the bladder cancer progression via AFF4/NF-κB/MYC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Jie, Wang, Jing-zi, Yang, Xiao, Yu, Hao, Zhou, Rui, Lu, Hong-Cheng, Yuan, Wen-Bo, Lu, Jian-chen, Zhou, Zi-jian, Lu, Qiang, Wei, Ji-Fu, Yang, Haiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588935/ https://www.ncbi.nlm.nih.gov/pubmed/31228940 http://dx.doi.org/10.1186/s12943-019-1036-9

Ejemplares similares

METTL3 mediates Ang-II-induced cardiac hypertrophy through accelerating pri-miR-221/222 maturation in an m6A-dependent manner
por: Zhang, Rui, et al.
Publicado: (2022)

METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner
por: Pan, Xiaoping, et al.
Publicado: (2021)

METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer
por: Sun, Kangyue, et al.
Publicado: (2023)

Down-Regulation of mir-221 and mir-222 Restrain Prostate Cancer Cell Proliferation and Migration That Is Partly Mediated by Activation of SIRT1
por: Yang, Xiao, et al.
Publicado: (2014)

METTL3 promotes colorectal cancer metastasis by promoting the maturation of pri-microRNA-196b
por: Huang, Lanlan, et al.
Publicado: (2022)

Role of miR-221/222 in Tumor Development and the Underlying Mechanism
por: Song, Qian, et al.
Publicado: (2019)

Microrna-221 and Microrna-222 Modulate Differentiation and Maturation of Skeletal Muscle Cells
por: Cardinali, Beatrice, et al.
Publicado: (2009)

Gastric Carcinogenesis in the miR-222/221 Transgenic Mouse Model
por: Choi, Boram, et al.
Publicado: (2017)

Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling
por: Chistiakov, Dmitry A., et al.
Publicado: (2015)

Influence of miR-221/222 on cardiomyocyte calcium handling and function
por: Knyrim, Maria, et al.
Publicado: (2021)

METTL3 promotes the initiation and metastasis of ovarian cancer by inhibiting CCNG2 expression via promoting the maturation of pri-microRNA-1246
por: Bi, Xuehan, et al.
Publicado: (2021)

METTL14 mediates m(6)a modification on osteogenic proliferation and differentiation of bone marrow mesenchymal stem cells by regulating the processing of pri-miR-873
por: Dong, Xin, et al.
Publicado: (2023)

Role of MicroRNAs-221/222 in Digestive Systems
por: Matsuzaki, Juntaro, et al.
Publicado: (2015)

Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases
por: Song, Jialin, et al.
Publicado: (2017)

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
por: Zhang, Chun-Zhi, et al.
Publicado: (2010)

miR-221/222 Target the DNA Methyltransferase MGMT in Glioma Cells
por: Quintavalle, Cristina, et al.
Publicado: (2013)

Genistein Promotes Skeletal Muscle Regeneration by Regulating miR-221/222
por: Shen, Linyuan, et al.
Publicado: (2022)

MiR-221/222 Ameliorates Deoxynivalenol-Induced Apoptosis and Proliferation Inhibition in Intestinal Epithelial Cells by Targeting PTEN
por: Hou, Lianjie, et al.
Publicado: (2021)

The inverted pattern of circulating miR-221-3p and miR-222-3p associated with isolated low HDL-C phenotype
por: Zhou, Yuntao, et al.
Publicado: (2018)

Reck-Notch1 Signaling Mediates miR-221/222 Regulation of Lung Cancer Stem Cells in NSCLC
por: Guo, Yuefan, et al.
Publicado: (2021)

miR-221/222 Promotes S-Phase Entry and Cellular Migration in Control of Basal-Like Breast Cancer
por: Li, Yuan, et al.
Publicado: (2014)

Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice
por: Jiang, Xiuli, et al.
Publicado: (2018)

HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer
por: Fu, Fangfang, et al.
Publicado: (2018)

TNC Accelerates Hypoxia-Induced Cardiac Injury in a METTL3-Dependent Manner
por: Cheng, Hao, et al.
Publicado: (2023)

Overexpression of primary microRNA 221/222 in acute myeloid leukemia
por: Rommer, Anna, et al.
Publicado: (2013)

MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
por: Chun-zhi, Zhang, et al.
Publicado: (2010)

The Inhibition of the Highly Expressed Mir-221 and Mir-222 Impairs the Growth of Prostate Carcinoma Xenografts in Mice
por: Mercatelli, Neri, et al.
Publicado: (2008)

In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma
por: Di Martino, Maria Teresa, et al.
Publicado: (2013)

miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases
por: Xu, Qinhong, et al.
Publicado: (2015)

miR-221/222 induce instability of p53 By downregulating deubiquitinase YOD1 in acute myeloid leukemia
por: Pei, Han Zhong, et al.
Publicado: (2023)

METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m(7)G-modified miR-760-dependent manner
por: Xie, Haiyun, et al.
Publicado: (2022)

METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner
por: Zhao, Kun, et al.
Publicado: (2021)

High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma
por: Zhang, Chunzhi, et al.
Publicado: (2012)

MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion
por: Falkenberg, N, et al.
Publicado: (2013)

HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer
por: Mardente, S., et al.
Publicado: (2015)

Expression and Change of miRs 145, 221 and 222 in Hypertensive Subjects Treated with Enalapril, Losartan or Olmesartan
por: Mandraffino, Giuseppe, et al.
Publicado: (2021)

Exosome‐delivered miR‐221/222 exacerbates tumor liver metastasis by targeting SPINT1 in colorectal cancer
por: Tian, Fei, et al.
Publicado: (2021)

Expression of lncRNA MIR222HG co-transcribed from the miR-221/222 gene promoter facilitates the development of castration-resistant prostate cancer
por: Sun, Tong, et al.
Publicado: (2018)

MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer
por: Shah, Maitri Y, et al.
Publicado: (2011)

Growth inhibitory effects of miR-221 and miR-222 in non-small cell lung cancer cells
por: Yamashita, Ryo, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_5tsbukv5tmm3eab4te2n3qervd