Cargando…
Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods
BACKGROUND: RNA sequencing offers advantages over other quantification methods for microRNA (miRNA), yet numerous biases make reliable quantification challenging. Previous evaluations of these biases have focused on adapter ligation bias with limited evaluation of reverse transcription bias or ampli...
Autores principales: | Wright, Carrie, Rajpurohit, Anandita, Burke, Emily E., Williams, Courtney, Collado-Torres, Leonardo, Kimos, Martha, Brandon, Nicholas J., Cross, Alan J., Jaffe, Andrew E., Weinberger, Daniel R., Shin, Joo Heon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588940/ https://www.ncbi.nlm.nih.gov/pubmed/31226924 http://dx.doi.org/10.1186/s12864-019-5870-3 |
Ejemplares similares
-
Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation
por: Price, Amanda J., et al.
Publicado: (2020) -
BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior
por: Maynard, Kristen R, et al.
Publicado: (2018) -
Altered expression of histamine signaling genes in autism spectrum disorder
por: Wright, C, et al.
Publicado: (2017) -
xMD-miRNA-seq to generate near in vivo miRNA expression estimates in colon epithelial cells
por: Rosenberg, Avi Z., et al.
Publicado: (2018) -
Significance analysis of lexical bias in microarray data
por: Kim, Charles C, et al.
Publicado: (2003)