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The HIF-1α/LC3-II Axis Impacts Fungal Immunity in Human Macrophages

The fungal pathogen Histoplasma capsulatum causes a spectrum of disease, ranging from local pulmonary infection to disseminated disease. The organism seeks residence in macrophages, which are permissive for its survival. Hypoxia-inducible factor 1α (HIF-1α), a principal regulator of innate immunity...

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Detalles Bibliográficos
Autores principales:	Friedrich, Dirk, Zapf, Dorinja, Lohse, Björn, Fecher, Roger A., Deepe, George S., Rupp, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589057/ https://www.ncbi.nlm.nih.gov/pubmed/31036602 http://dx.doi.org/10.1128/IAI.00125-19

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