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Innervation of Thermogenic Adipose Tissue via a Calsyntenin-3β/S100b Axis
The sympathetic nervous system drives brown and beige adipocyte thermogenesis via release of norepinephrine from local axons. However, the molecular basis underlying the higher levels of sympathetic innervation of thermogenic fat, compared to white fat, has remained elusive. Here we show that thermo...
Autores principales: | Zeng, Xing, Ye, Mengchen, Resch, Jon M., Jedrychowski, Mark P., Hu, Bo, Lowell, Bradford B., Ginty, David D., Spiegelman, Bruce M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589139/ https://www.ncbi.nlm.nih.gov/pubmed/31043739 http://dx.doi.org/10.1038/s41586-019-1156-9 |
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