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Hypoxia-Inducible Factor-1α Knockdown Plus Glutamine Supplementation Attenuates the Predominance of Necrosis over Apoptosis by Relieving Cellular Energy Stress in Acute Pancreatitis
The present study was conducted to investigate the effect and potential mechanism of hypoxia-inducible factor-1α (HIF-1α) genetic inhibition plus glutamine (Gln) supplementation on necrosis-apoptosis imbalance during acute pancreatitis (AP), with a specific focus on the regulations of intracellular...
Autores principales: | Ji, Liang, Guo, Xiaoyu, Lv, Jiachen, Xiao, Fan, Zhang, Wangjun, Li, Jie, Lin, Zhitao, Sun, Bei, Wang, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589200/ https://www.ncbi.nlm.nih.gov/pubmed/31281575 http://dx.doi.org/10.1155/2019/4363672 |
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