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AKT-GSK3β Signaling Pathway Regulates Mitochondrial Dysfunction-Associated OPA1 Cleavage Contributing to Osteoblast Apoptosis: Preventative Effects of Hydroxytyrosol

Oxidative stress (OS) induces osteoblast apoptosis, which plays a crucial role in the initiation and progression of osteoporosis. Although OS is closely associated with mitochondrial dysfunction, detailed mitochondrial mechanisms underlying OS-induced osteoblast apoptosis have not been thoroughly el...

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Detalles Bibliográficos
Autores principales: Cai, W. J., Chen, Y., Shi, L. X., Cheng, H. R., Banda, I., Ji, Y. H., Wang, Y. T., Li, X. M., Mao, Y. X., Zhang, D. F., Dai, P. P., Sun, X. Y., Ning, X. H., Huang, S. B., Ma, J. F., Zhao, S. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589274/
https://www.ncbi.nlm.nih.gov/pubmed/31281574
http://dx.doi.org/10.1155/2019/4101738

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