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AKT-GSK3β Signaling Pathway Regulates Mitochondrial Dysfunction-Associated OPA1 Cleavage Contributing to Osteoblast Apoptosis: Preventative Effects of Hydroxytyrosol
Oxidative stress (OS) induces osteoblast apoptosis, which plays a crucial role in the initiation and progression of osteoporosis. Although OS is closely associated with mitochondrial dysfunction, detailed mitochondrial mechanisms underlying OS-induced osteoblast apoptosis have not been thoroughly el...
Autores principales: | Cai, W. J., Chen, Y., Shi, L. X., Cheng, H. R., Banda, I., Ji, Y. H., Wang, Y. T., Li, X. M., Mao, Y. X., Zhang, D. F., Dai, P. P., Sun, X. Y., Ning, X. H., Huang, S. B., Ma, J. F., Zhao, S. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589274/ https://www.ncbi.nlm.nih.gov/pubmed/31281574 http://dx.doi.org/10.1155/2019/4101738 |
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