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Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex
Efficient transfer of sensory information to higher (motor or associative) areas in primate visual cortical areas is crucial for transforming sensory input into behavioral actions. Dynamically increasing the level of coordination between single neurons has been suggested as an important contributor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589668/ https://www.ncbi.nlm.nih.gov/pubmed/31147468 http://dx.doi.org/10.1073/pnas.1819827116 |
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author | Khamechian, Mohammad Bagher Kozyrev, Vladislav Treue, Stefan Esghaei, Moein Daliri, Mohammad Reza |
author_facet | Khamechian, Mohammad Bagher Kozyrev, Vladislav Treue, Stefan Esghaei, Moein Daliri, Mohammad Reza |
author_sort | Khamechian, Mohammad Bagher |
collection | PubMed |
description | Efficient transfer of sensory information to higher (motor or associative) areas in primate visual cortical areas is crucial for transforming sensory input into behavioral actions. Dynamically increasing the level of coordination between single neurons has been suggested as an important contributor to this efficiency. We propose that differences between the functional coordination in different visual pathways might be used to unambiguously identify the source of input to the higher areas, ensuring a proper routing of the information flow. Here we determined the level of coordination between neurons in area MT in macaque visual cortex in a visual attention task via the strength of synchronization between the neurons’ spike timing relative to the phase of oscillatory activities in local field potentials. In contrast to reports on the ventral visual pathway, we observed the synchrony of spikes only in the range of high gamma (180 to 220 Hz), rather than gamma (40 to 70 Hz) (as reported previously) to predict the animal’s reaction speed. This supports a mechanistic role of the phase of high-gamma oscillatory activity in dynamically modulating the efficiency of neuronal information transfer. In addition, for inputs to higher cortical areas converging from the dorsal and ventral pathway, the distinct frequency bands of these inputs can be leveraged to preserve the identity of the input source. In this way source-specific oscillatory activity in primate cortex can serve to establish and maintain “functionally labeled lines” for dynamically adjusting cortical information transfer and multiplexing converging sensory signals. |
format | Online Article Text |
id | pubmed-6589668 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | National Academy of Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-65896682019-06-27 Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex Khamechian, Mohammad Bagher Kozyrev, Vladislav Treue, Stefan Esghaei, Moein Daliri, Mohammad Reza Proc Natl Acad Sci U S A PNAS Plus Efficient transfer of sensory information to higher (motor or associative) areas in primate visual cortical areas is crucial for transforming sensory input into behavioral actions. Dynamically increasing the level of coordination between single neurons has been suggested as an important contributor to this efficiency. We propose that differences between the functional coordination in different visual pathways might be used to unambiguously identify the source of input to the higher areas, ensuring a proper routing of the information flow. Here we determined the level of coordination between neurons in area MT in macaque visual cortex in a visual attention task via the strength of synchronization between the neurons’ spike timing relative to the phase of oscillatory activities in local field potentials. In contrast to reports on the ventral visual pathway, we observed the synchrony of spikes only in the range of high gamma (180 to 220 Hz), rather than gamma (40 to 70 Hz) (as reported previously) to predict the animal’s reaction speed. This supports a mechanistic role of the phase of high-gamma oscillatory activity in dynamically modulating the efficiency of neuronal information transfer. In addition, for inputs to higher cortical areas converging from the dorsal and ventral pathway, the distinct frequency bands of these inputs can be leveraged to preserve the identity of the input source. In this way source-specific oscillatory activity in primate cortex can serve to establish and maintain “functionally labeled lines” for dynamically adjusting cortical information transfer and multiplexing converging sensory signals. National Academy of Sciences 2019-06-18 2019-05-30 /pmc/articles/PMC6589668/ /pubmed/31147468 http://dx.doi.org/10.1073/pnas.1819827116 Text en Copyright © 2019 the Author(s). Published by PNAS. https://creativecommons.org/licenses/by-nc-nd/4.0/ https://creativecommons.org/licenses/by-nc-nd/4.0/This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | PNAS Plus Khamechian, Mohammad Bagher Kozyrev, Vladislav Treue, Stefan Esghaei, Moein Daliri, Mohammad Reza Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex |
title | Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex |
title_full | Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex |
title_fullStr | Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex |
title_full_unstemmed | Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex |
title_short | Routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex |
title_sort | routing information flow by separate neural synchrony frequencies allows for “functionally labeled lines” in higher primate cortex |
topic | PNAS Plus |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589668/ https://www.ncbi.nlm.nih.gov/pubmed/31147468 http://dx.doi.org/10.1073/pnas.1819827116 |
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