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Expression of TorsinA in a heterologous yeast system reveals interactions with lumenal domains of LINC and nuclear pore complex components

DYT1 dystonia is caused by an in-frame deletion of a glutamic acid codon in the gene encoding the AAA+ ATPase TorsinA (TorA). TorA localizes within the lumen of the nuclear envelope/endoplasmic reticulum and binds to a membrane-spanning cofactor, lamina associated polypeptide 1 (LAP1) or lumenal dom...

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Detalles Bibliográficos
Autores principales:	Chalfant, Madeleine, Barber, Karl W., Borah, Sapan, Thaller, David, Lusk, C. Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2019
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589686/ https://www.ncbi.nlm.nih.gov/pubmed/30625036 http://dx.doi.org/10.1091/mbc.E18-09-0585

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