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Role of JAM-A tyrosine phosphorylation in epithelial barrier dysfunction during intestinal inflammation
Junctional adhesion molecule-A (JAM-A), an epithelial tight junction protein, plays an important role in regulating intestinal permeability through association with a scaffold signaling complex containing ZO-2, Afadin, and the small GTPase Rap2. Under inflammatory conditions, we report that the cyto...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589701/ https://www.ncbi.nlm.nih.gov/pubmed/30625033 http://dx.doi.org/10.1091/mbc.E18-08-0531 |