Local, transient tensile stress on the nuclear membrane causes membrane rupture

Cancer cell migration through narrow constrictions generates compressive stresses on the nucleus that deform it and cause rupture of nuclear membranes. Nuclear membrane rupture allows uncontrolled exchange between nuclear and cytoplasmic contents. Local tensile stresses can also cause nuclear deform...

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Detalles Bibliográficos
Autores principales: Zhang, Qiao, Tamashunas, Andrew C., Agrawal, Ashutosh, Torbati, Mehdi, Katiyar, Aditya, Dickinson, Richard B., Lammerding, Jan, Lele, Tanmay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589786/
https://www.ncbi.nlm.nih.gov/pubmed/30566037
http://dx.doi.org/10.1091/mbc.E18-09-0604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589786/
https://www.ncbi.nlm.nih.gov/pubmed/30566037
http://dx.doi.org/10.1091/mbc.E18-09-0604

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