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Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs

Eukaryotic initiation factor 2 (eIF2) is a G protein critical for translation. It is tightly regulated in the integrated stress response (ISR) via phosphorylation of eIF2α and the subsequent control of eukaryotic initiation factor 2B (eIF2B), a multisubunit guanine nucleotide exchange factor. Throug...

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Detalles Bibliográficos
Autores principales:	Hodgson, Rachel E., Varanda, Beatriz A., Ashe, Mark P., Allen, K. Elizabeth, Campbell, Susan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589909/ https://www.ncbi.nlm.nih.gov/pubmed/30726166 http://dx.doi.org/10.1091/mbc.E18-08-0538

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