P465L‐PPARγ mutation confers partial resistance to the hypolipidaemic action of fibrates

AIMS: Familial partial lipodystrophic syndrome 3 (FPLD3) is associated with mutations in the transcription factor PPARγ. One of these mutations, the P467L, confers a dominant negative effect. We and others have previously investigated the pathophysiology associated with this mutation using a humaniz...

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Detalles Bibliográficos
Autores principales: Rodriguez‐Cuenca, Sergio, Carobbio, Stefania, Barceló‐Coblijn, Gwendolyn, Prieur, Xavier, Relat, Joana, Amat, Ramon, Campbell, Mark, Dias, Ana Rita, Bahri, Myriam, Gray, Sarah L., Vidal‐Puig, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589924/
https://www.ncbi.nlm.nih.gov/pubmed/29790245
http://dx.doi.org/10.1111/dom.13370

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