Pharmacokinetics and tolerability of inhaled levodopa from a new dry-powder inhaler in patients with Parkinson’s disease

BACKGROUND: Inhaled levodopa may quickly resolve off periods in Parkinson’s disease. Our aim was to determine the pharmacokinetics and tolerability of a new levodopa dry-powder inhaler. METHODS: A single-centre, single-ascending, single-dose–response study was performed. Over three visits, eight Par...

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Detalles Bibliográficos
Autores principales: Luinstra, Marianne, Rutgers, Wijnand, van Laar, Teus, Grasmeijer, Floris, Begeman, Anja, Isufi, Valmira, Steenhuis, Luc, Hagedoorn, Paul, de Boer, Anne, Frijlink, Henderik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589987/
https://www.ncbi.nlm.nih.gov/pubmed/31258882
http://dx.doi.org/10.1177/2040622319857617

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